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Multiple randomized controlled trials have shown that lipoic acid may benefit people who suffer from migraines

Clinical improvement was also observed in oxidative stress markers, with improvements in methionine levels (p=0.05), homocysteine levels (SAH, p=0.007) and the ratio of S-adenosylmethionine (SAMe) to SAH (p=0.007), indicating improvement with methylation at the cellular level and a decrease in oxidative stress in the body 2

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The Phase 2 clinical trial showed roughly 2-3 kg more fat loss than placebo over 12 weeks, with no impact on blood sugar, insulin, IGF-1, or any hormonal marker