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Citations Citations to this article as recorded by Comparative Clinical Analysis of DPP-4 inhibitors and SGLT2 Inhibitors: A Real-World Switch Study Hun Jee Choe, Mi Kyung Kwak, Ji Woo Lee, Yun Mi Choi, Eun-Gyoung Hong Journal of Obesity & Metabolic Syndrome.2026

How these weight-loss drugs may reduce heart attack and stroke risk GLP1 medications have become widely known for helping people lose weight, but before they made headlines for weight management, researchers were studying them for something even more important: protecting the heart

doi: 10.1016/j.canlet.2013.02.032 66

What happens instead is that the brain (hypothalus) keeps telling the body, youre starving, you need food, and the drive to find food overrides everything else

Weekly rates faster than 2 pounds often indicate: Unrealistic calorie restrictions High risk of muscle loss Potential metabolic slowdown Difficulty maintaining long-term If your calculator suggests faster loss, consider extending your timeline for better sustainability