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Esta regulacin es bidireccional: el pptido puede aumentar o disminuir la produccin de NO segn el contexto patolgico, contribuyendo as a la proteccin vascular y a la reduccin de la inflamacin

57(Suppl 6): 17-42

Representative domains include: Gastrointestinal and hepatic models: Protection against ulcers, leaky gut, IBSlike symptoms, Crohntype inflammation, and toxic liver injury (e.g., CCl4, NSAID, and alcohol models), with improved mucosal healing and barrier integrity

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It is also sometimes used off-label for skin lightening, though evidence for this indication is limited