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Once phosphorylated the tyrosine residues of the beta subunit serve as docking sites for downstream signaling mediators including extracellular signal-regulated kinase (ERK) and the phosphatidylinositol-3-kinase (P13K) pathway [78] ( Figure 2 )

doi:10.1016/S0140-6736(17)31585-4 271

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International Journal of Peptide Science , 14(3), 117126

Increasing insulin release Lowering the amount of glucagon released Delaying gastric emptying Reducing appetite Can GLP1 medications be used for diabetes and weight loss together