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Children aged 412 years were diagnosed with ASD according to DSM criteria, both boys and girls were included, and the study explicitly excluded participants with major psychiatric comorbidities such as ADHD, depressions, bipolar disorder, anxiety disorders, epilepsy, severe intellectual disabilities, or recent antipsychotic use, ensuring relative homogeneous sample focused on irritability
Phenotype analyses showed increased sensitivities of bsh mutants toward hypochlorite, diamide, methylglyoxal, ROS (paraquat, H 2 O 2 ), osmotic, and acidic stress, alkylating agents and fosfomycin in B
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