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Arab journal of urology

10.1016/j.cell.2021.09.005 Cell 176 WangQ.ZhengJ.PetterssonS.ReynoldsR.TanE

The pivotal Phase 2 trial a 48-week study published in The New England Journal of Medicine in 2023 produced these results in adults with obesity (and no diabetes), at the highest dose of 12 mg weekly: Average weight loss of around 24% from baseline A clear dose-response, with even the 4 mg dose producing roughly 17% weight loss Continued weight loss right up to the 48-week endpoint, with no plateau in sight For context, similar Phase 2 data for Wegovy showed around 15% weight loss at 68 weeks

The Cost Factor and Financial Planning The cost varies depending on the program, medication, and duration

There is little research regarding the association of Se and F2-isoP levels or the effects of Se supplementary use