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While it may not be completely inert, its potency and stability have been significantly reduced

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It can also occur as a reaction to sudden dietary changes made while on the medication

Although the exact signaling pathways are not fully understood, it is often suggested that the pro-opiomelanocortin (POMC)-derived melanocortin peptides, including compounds analogous to a-melanocyte-stimulating hormone (a-MSH), may influence neuronal structures by increasing the number and length of neurites and potentially promoting nerve sprouting in damaged regions