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Classical cirrhosis is rare in rodents in contrast to dogs and humans and cannot reliably or consistently separate from a robust fibrotic reaction with associated nodular regeneration, oval cell proliferation, and bile duct hyperplasia

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[27] The 13mcg (520 IU) dose in this supplement provides meaningful support for maintaining muscle mass, but without going overboard, since excess vitamin D3 use can lead to soft tissue calcification

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