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First described in 2012, Dixon et al 11 explained that ferroptosis is an iron-dependent programmed nonapoptotic cell death with unique biological processes and pathophysiologic characteristics

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The recommended dose of GBS01 was therefore determined to be 4 g of burdock fruit extract, as no dose-limiting toxicity were observed at any dose levels tested

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doi:10.1093/jrr/rrw054 20