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G lucagon-like peptide 1 receptor agonists (GLP-1RA), a class of medication originally approved for diabetes 1 and now also approved for weight management in patients with obesity, 2 have grown exponentially in popularity over the past few years

Berberine may influence fat storage and metabolism through various pathways, whilst L-carnitine's role in fat oxidation has led to interest in its potential for body composition

However, recent focus on Nrf2 and the Proteasome offer promising new avenues for maintaining allostasis and avoiding allostatic overload associated with anxiety disorders

Park et al., 2012

Hormone Research (2000) 5