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The two peptides are clinically synergistic. No controlled combination trial was identified

English search terms included: diabetic kidney disease OR diabetic nephropathy OR DKD OR DN, combined with gut microbiota OR gut microbiome OR intestinal flora OR intestinal microbiota, dietary OR nutrition OR diet OR nutritional intervention, phytochemical OR natural product OR bioactive compound OR functional food, amino acid metabolism OR metabolite OR metabolomics, gut-liver axis OR gut-kidney axis OR enterohepatic axis, short-chain fatty acids OR SCFAs, and probiotics OR prebiotics OR synbiotics. Inclusion criteria were: (1) studies addressing the associations among DKD, gut microbiota, nutritional intervention, and natural bioactive compounds

With BPC-157 and TB-500, human data are limited, and individual responses vary

Tully J, Petrinovic MM

Protective Effect of Sulforaphane against Dopaminergic Cell Death