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doi: 10.1016/j.biopha.2019.109249 22 ZiaAFarkhondehTPourbagher-ShahriAMSamarghandianS

Notably, despite its synthesis occurring primarily in the cytosol, previous studies have demonstrated that mitochondria contain approximately 1015% of the total cellular GSH [28], suggeSlc25a39 the existence of a transport system that facilitates GSH import into these organelles

Unlike the DAC-conjugated version, the no-DAC form lacks the albumin-binding linker and is studied as a short-acting GRF analog

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It has been revealed that prolonged exposure to stress triggers biological mechanisms, in particular those related to the regulation of the inflammatory cascade, which plays a key role in the pathogenesis of many diseases