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(II) Despite the intracellular GSH being significantly consumed in the cases stated in this review, it is difficult to completely deplete GSH via these strategies

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Khavinson VK, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B

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Some studies suggest that introducing healthy mitochondria into cancer cells can enhance their sensitivity to ferroptosis inducers [174], while other studies indicate that mitochondrial fusion may activate protective metabolic axes (e.g., Nrf2), thereby promoting tumor growth [175]