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doi: 10.1136/bmj.f5061

"The FDA's compounding program aims to protect patients from poor quality compounded drugs, while preserving access to lawfully marketed compounded drugs for patients." Compound versions of drugs -- made for individual patients using raw ingredients -- are not required to go through the FDA's rigorous approval process

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and/or patients with a high metabolic burden who have already entered the fertility pathway but encountered metabolic-related barriers during ART (e.g., high OHSS risk, suboptimal oocyte/embryo quality, or cycle cancelation)