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Both preclinical and clinical studies support that the gastric slowing that occurs with tirzepatide is due to GLP-1R agonism and not related to GIPR agonism [15]

Despite these resources, demand for GLP-1 medications like tirzepatide has outpaced local capacity since the FDA approval of Zepbound in November 2023 - driving many Atlanta residents to telehealth providers for faster access

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24 GLP-1 RAs are an antidiabetic class of drugs, but their effect on the relative reduction in HbA1c compared with placebo was moderate (0.41.2%) in the cardiovascular outcomes trials (CVOTs)