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Retatrutide has no UK marketing authorisation and is not available through the NHS or regulated pharmacies

In patients without diabetes, tirzepatide provided an additional 3.6% weight loss compared to semaglutide, while in patients with diabetes, the percentage change in body weight was not statistically different between the two groups

Who Might Benefit: The 6.6 Million Estimate A Yale team analyzed national registries to mirror SELECT trial eligibility and estimated that about 6.6 million Americans have obesity or overweight and established cardiovascular disease, but not diabetes