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Novo Nordisk offers Wegovy to patients without insurance for $499 per month through its direct-to-consumer platform, NovoCare Pharmacy

It is part of the GLP-1 receptor agonist class of drugs, similar to medications like Ozempic and Rybelsus, but is manufactured by Eli Lilly and Company

The impact we are seeing in OA might be real, but we have to define it more clearly. Although no data are conclusive yet, preclinical studies have shown that GLP-1 receptor agonists can inhibit the NF-kB pathway, a key pathway involved in inflammation and cartilage destruction, according to Lane

( PMID: 23324757 ) Benzaquen M, Borradori L, Berbis P, Cazzaniga S, Valero R, Richard MA, Feldmeyer L (2018) Dipeptidyl peptidase IV inhibitors, a risk factor for bullous pemphigoid: retrospective multicenter case-control study from France and Switzerland

Sublingual: Liquid dropped under the tongue daily