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Singh A, Rangasamy T, Thimmulappa RK, et al

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The drug has endured numerous clinical trials, one of the largest of which saw a 15.8% reduction in body weight after 68 weeks.7 For a 250lb person, that would equate to a loss of 39.5 pounds in a little over a year

This hypothesis is consistent with the observation that activation of liver X receptors (LXR) prevented APAP-induced liver injury through induction of phase II conjugating enzymes, as well as suppression of pro-toxic phase I P450 enzymes [103]