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Full-length thymosin beta-4, formulated as a topical ophthalmic solution (RGN-259), has been evaluated in genuine Phase II randomized, placebo-controlled human trials for dry eye disease

[1] The Human Evidence Gap and Where Research Is Heading The most intellectually honest statement about BPC-157 is this: an unusually robust preclinical literature has established a plausible and broadly consistent mechanistic picture, while the human clinical trial evidence remains essentially absent

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The shared theme is angiogenesis : both have been reported to promote the formation of new blood vessels, which is a plausible contributor to tissue repair because new tissue needs a blood supply