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Before menopause, human estrogen biosynthesis occurs largely in the ovary and the testis, adipose tissue, brain, adrenals, skin, and bones (Taves et al., 2011

It is even available in injectable form

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Although there is no cause-and-effect relationship between microbial composition and disease propensity, the microbiome is a major contributor in several disease states, an approach that is attracting scientific attention presently (Islam et al., 2022), obesity (Rahman et al., 2022d), cancer (Rahman et al., 2022a), allergic asthma (McKenzie et al., 2017), and others

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