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Meals are planned to begin with protein-rich foods so that adequate protein is consumed despite reduced hunger, which helps protect muscle mass during weight loss 8

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Additionally, indole-3-carboxylic acid (ICA), a metabolite derived from Lactobacillus gallinarum , has been shown to improve anti-PD-1 efficacy in mouse models with different microsatellite instability (MSI) statuses [104]

For aging adults, consistent butyrate support , whether through increased fiber intake or direct supplementation, appears to be a valuable strategy for maintaining quality of life and supporting healthy aging