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Individuals with existing liver disease should consult their GP before regularly consuming organ meats, as impaired hepatic function may affect vitamin A metabolism and storage

Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

Methylmalonic Acid Homocysteine Notes on Clinical Trials of B12 Supplementation Although not addressed in the graphs, younger people who start out deficient tend to have more drastic, initial drops in MMA and homocysteine