While modafinil itself has been studied extensively and approved for specific medical uses, its analogues have not
Getting Started Eligibility: Standard criteria apply regardless of sex: BMI 30 or higher, OR BMI 27 or higher with a weight-related condition (hypertension, diabetes, sleep apnea, etc.) Accessing treatment: Options include: Primary care physicians Endocrinologists or obesity medicine specialists Telehealth platforms like TrimRx Cost considerations: Brand-name Ozempic/Wegovy: $349/month through manufacturer cash-pay programs Compounded semaglutide: $199/month through TrimRx For detailed cost information, see our guide on compounded semaglutide costs
Why This Matters: Excess body weight is a major contributor to joint stress and inflammation, leading to conditions like osteoarthritis
Starting at a low dose and increasing gradually minimizes side effects
Once-weekly semaglutide use in patients with type 2 diabetes: results from the SURE Spain multicentre, prospective, observational study