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Cappetta, D., (2017)

2.10 Overexpression and knockdown of RRM2 gene in TPC-1 and IHH4 cells For upregulating RRM2 expression in cells, we obtained a full-length RRM2 sequence fragment using a PCR method and subsequentlycloned it into vector LV18, verified by DNA sequencing and transfected 293T cells (see Supplementary Materials for details)

10.1016/j.ymgme.2007.08.122 Mol Genet Metab

Importantly, vitamin B 6 deficiency is linked to neurological dysregulation, renal impairment and autoimmune disorders, making it as a promising prophylactic and therapeutic agent against pathogenic infections 19

Freeze the lyophilized vial