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Common side effects include nausea, vomiting, and diarrhoea, particularly during dose escalation

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Packer M et al., SUMMIT, NEJM 2024 (NEJMoa2410027, PMID 39555826) : tirzepatide and HFpEF with obesity, HR 0,62 composite endpoint

According to Mankin et al, the rigorousness of the OA destruction was categorized using the histologic standards (Table 2) based on structural variations (scale range 06), cellular variations (scale range 03), damage of safranin O staining (scale range 04) and tidemark integrity (scale range 01) by 3 independent researchers

Older adults with less acid in their stomachs In addition, the dosage of B12 is based on the medical condition and response to treatment