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Recently, despite a lack of significant association between hyperhomocysteinemia and the risk of venous thromboembolism, in a prospective study of patients with systemic lupus erythematosus, Petri et al (1996) report that hyperhomocysteinemia, defined as total plasma homocysteine concentrations higher than 14.1 mol/L, is significantly associated with arterial thrombotic events (odds ratio 3.74), and stroke (odds ratio 2.24)

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MedicalDaily Evidence Check The evidence base for BPC-157, TB-500, and MOTS-C consists of animal studies, small pilot human trials, and anecdotal clinical reports, none of which meet the standard of a Phase 3 randomized controlled trial required for FDA drug approval