semaglutide kept in fridge Don't Risk It: Store Pens, Vials & Tablets Right Semaglutide Storage Guide: How Long

According to Truveta Research presented at ISPOR 2025, side effects were the leading reason patients stopped taking GLP-1 medications, accounting for 28.2% of all discontinuations

Patients with Thyroid Cancer History: Those with personal or family history of specific thyroid cancers should not take semaglutide due to potential risks

If the patient is experiencing gastrointestinal symptoms, EMS personnel should assess for recent increase in dose with their prescribed semaglutide medications, as increasing the dose of semaglutide medications may trigger gastrointestinal symptoms

All three share similar GI side effects nausea, diarrhea, vomiting because all target the GLP-1 receptor

Most people find they feel satisfied with smaller portions and experience fewer intense cravings