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A 26-week diabetes study measured human activity at 1 mg, but its endpoint was blood sugar rather than long-term weight. A short outpatient cohort measured about 4.7% weight loss over four weeks at 2.5 mg. Below 1 mg, estimates rely on pharmacokinetics and mechanism

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doi: 10.1038/s41598-017-08935-6 104 BoffDCrijnsHJanssensRVanheuleVMenezesGBMacariSet al

[1] Removing the needle too quickly can result in medication leakage, reducing the delivered dose

About Tesofensine: Ttesofensine a medicine that helps people lose extra weight