For acute shoulder injuries causing significant pain, split dosing at 0.25mg twice daily may produce better results than 0.5mg once daily despite the same total amount
To meet the diagnostic criteria for cvEDS, a person must meet: Major criterion 1 AND family history compatible with autosomal recessive inheritance AND at least one other major criterion OR Major criterion 1 AND family history compatible with autosomal recessive inheritance AND at least two minor criteria Major Criteria Severe progressive cardiac-valvular problems (aortic valve, mitral valve) Skin involvement: skin hyperextensibility, atrophic scars, thin skin, easy bruising Joint hypermobility (generalized or restricted to small joints) Minor criteria Inguinal hernia Pectus deformity (especially excavatum) Joint dislocations Foot deformities: pes planus, pes planovalgus, hallux valgus Classical-like EDS (clEDS) If a person meets the diagnostic criteria for clEDS, genetic testing should be done to confirm the diagnosis

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Crucial Distinction: This upcoming meeting is not an FDA drug approval process
doi: 10.3389/fimmu.2018.02537 88 HongKHChoMLMinSYShinYJYooSAChoiJJet al