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Liproxstatin-1 has shown potential in preclinical models of lung injury by reducing oxidative damage, inflammation, and vascular permeability (103)

Transforming growth factor-1 inhibits interleukin-1-induced expression of inflammatory genes and cathepsin S activity in human vascular smooth muscle cells

Brain health should also be incorporated, using cognitive testing and imaging to assess whether these therapies influence neurodegenerative risk

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PubMed, Ratajewski, Marcin, et al