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This analysis also echoes the researchers comment that the drug has never been tested in humans and would require careful considerations of safety

Studies tracking generic drug prices since the late 2000s show that many commodity generics are priced at a fraction of their levels a decade ago the result of aggressive purchasing by pharmacy chains, PBMs, and group purchasing organizations (GPOs), combined with increasing consolidation among buyers and global supply chain expansion [31]

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Niacinamide may be used by adults with melasma or hyperpigmentation, including those with sensitive or reactive skin