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In DSS-induced and TNBS-induced colitis models, oral KPV significantly reduced disease severity, colonic inflammation, and pro-inflammatory cytokine expression

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EtOH also activates sterol regulatory binding protein1C (SREBP1C), a transcription factor which regulates lipogenic gene expression in the liver, further contributing to lipid accumulation (Osna et al., 2017)

Most of the available evidence was generated in animal studies

Vitamin C deficiency and its association with psychiatric effects have been known for many years