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61 A working core outcome set for CLE trials was recently developed to guide future clinical and outcomes research in CLE, recommending the CLASI as a primary endpoint and the Cutaneous Lupus Activity IGA (CLA-IGA) as a secondary endpoint for CLE physician-reported outcome measures

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Locally, there is no DPP-4 expression in taste tissue, which could suggest that in this location, GLP-1 may achieve a longer half-life (167)

It was designed as a modified version of the C-terminal portion of human growth hormone (hGH)

Week 13 onward: 10 mg weekly, with potential increase to 12.5 mg or 15 mg based on response and tolerability