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The production of oxylipins from tissue PUFAs depends on both the dietary intake of these fatty acids and their local availability for incorporation into cell membrane phospholipids during metabolic processing (55)

DDDL reviewed literature and edited the manuscript

Other contributors to this work include Premranjan Kumar, Chun Liu, James W

G.QuarantaD.DomailleD

A Shimadzu LC20AD, Ultra Performance Liquid Chromatography (UPLC) system (Shimadzu Corporation, Kyoto, Japan) equipped with Shimadzu 8040 triple quadrupole (QqQ) mass analyzer (Shimadzu Corporation, Kyoto, Japan) with an electrospray ionization source (ESI) operated in the positive charge mode for the quantification of 1 and 2