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The recommended intake for smokers is 35 mg/day higher than for non-smokers, because smokers are under increased oxidative stress from the toxins in cigarette smoke and generally have lower blood levels of vitamin C (see Table 7 reference [41])

People with bleeding disorders or taking blood thinning medications should avoid taking NAC because it may slow the blood clotting process

these drugs may have improved efficacy and reduced adverse effect profiles, providing much needed therapeutic choice before considering irreversible sub-total pancreatectomy as a last resort for the treatment of severe and recurrent hypoglycaemia

reported that SI also stimulates mitochondrial ROS production and promotes ferroptosis in RPECs (175)

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