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Phosphorylation of eIF2 leads to inhibition of general protein synthesis, but paradoxically increases the translation of selective mRNA such as ATF4 16

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9.3 Asthma and allergic rhinitis Apigenin demonstrated the ability to attenuate allergen-induced airway inflammation in a murine model of OVA-induced asthma, decreasing the degree of inflammatory cell infiltration, airway hyperresponsiveness, total IgE levels, and demonstrating a Th1 profile [136]