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Apolipoprotein E \({\varvec{\varepsilon \) 4 is also known to exacerbate tau neurofibrillary tangle-related neurodegeneration, microglial responses and neuroinflammation, astroglial activity, and blood brain barrier disruption [82]

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In response, the pancreas releases insulin to signal cells to absorb that glucose and use it for energy

N6-methyladenosine (m6A) stands as the most common RNA modification in gene expression regulation, significantly contributing to diverse biological processes within cells [8]