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These pathways are involved in metabolic regulation, energy expenditure, glucose control, and appetite signalling

[DOI] [PMC free article] [PubMed] [Google Scholar] [128].Khafipour E, Krause DO, Plaizier JC

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Wegovy, whilst more effective (average 10-15% weight loss in clinical trials), is reserved for specific circumstances and is only available through NHS specialist Tier 3 weight management services for people meeting specific criteria under TA875, with treatment limited to a maximum of 2 years