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Studies suggest subclinical hypothyroidism affects anywhere between 410% of the general population, with significantly higher rates in women and in people over 60 (NIH)
This trial is ongoing and the results will provide robust evidence of the impact of various bariatric surgical procedures on long-term glycaemic control and T2DM remission [35, 36]
Finally, a recent network meta-analysis that compared cognitive outcomes with various antidiabetic agents in patients with type 2 diabetes observed that GLP-1RAs ranked second after sodium-glucose cotransporter-2 inhibitors for reducing dementia risk
Given the recognized window of opportunity in early PsA, future research should prioritize trials in patients with subclinical joint involvement, arthralgia, or early enthesitis, especially those with coexisting obesity or MetS
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