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Excess fumarate, resulting from impaired TCA function, accumulates in the cytoplasm and reacts with thiol groups in crucial cellular proteins, leading to succination and inactivation [81, 82]

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Live cell imaging results showed that some cells exhibited a state of non-division or nonextension under Gln deficiency (Gln) conditions, whereas cells grew plum and well under Gln sufficiency (Gln+) conditions (Fig

Furthermore, it promotes lean mass gain, protein synthesis, increased bone density, and improved sleep

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