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This assay exploits the fluorometric properties of NADP + generated from GSSG oxidation during the GPx reaction, providing enhanced sensitivity compared to spectrophotometric methods

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5.2 Bone pain-related diseases Targeted ferroptosis for OA treatment principally focuses on reducing iron levels, and iron chelators, including deferoxamine (DFO), deferasirox (DFX), and deferiprone (DFP) have been used clinically (111, 140)

Most evidence is preliminary

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