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Synergistic combined effect of drugs induces cell cycle arrest, apoptosis, and alteration to mitochondrial membrane potential in cancer cells as well as down regulates the expression of CD44 receptor, which are main factor for cancer metastasis

A meta-analysis conducted by Yao et al

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The difference between elevated or unchanged GLP-1 levels in obese patients may be related to differences in metabolic status and detection methods, but the significant correlation between GLP-1 and lipid metabolism suggests that it can control weight and regulate lipid metabolism in HF diet groups, and GLP-1 has the potential to treat obesity caused by HF diet [102]