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Side effects are usually minor and short-lived
The induction of ferroptosis is tied to lipid peroxidation, amino acid metabolism, and iron metabolism, and has been linked to conditions including myocardial ischemia/reperfusion (MI/R), cardiac hypertrophy, cardiomyopathy, atherosclerosis, heart failure, and abdominal aortic aneurysm
On one hand, neutrophils significantly contribute to immune dysregulation and tissue damage through the formation of neutrophil extracellular traps (NETs), which are rich in decondensed nucleic acids and expel chromatin that can trigger specific autoreactive immune responses to nucleic acid antigens (79, 80)