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Currently available The Incretin hormones released by the gut, gastric inhibitory peptide (GIP) and Glucagon like peptide1 (GLP-1) (liraglutide) stimulate insulin secretion upon nutrient entry into the gut, suppression of glucagon release,slow gastric emptying and decrease food intake [128, 129]

In terms of reduction in total LDL levels, 9 studies (with 325 and 288 subjects from the experimental and control groups, respectively) were included for analysis

PQQ is an antioxidant, and based on research, it seems to be more powerful at fighting free radicals than vitamin C

real-world studies also suggest higher rates of discontinuation and intermittent use ( 5.2 Rare serious adverse events: individualized screening and monitoring Gallbladder disease: GLP-1RAs are associated with an increased risk of gallbladder-related events, often occurring in parallel with mechanisms such as rapid weight loss and cholestasis ( Pancreatitis and Medullary Thyroid Carcinoma (MTC): while existing evidence has not established a definitive causal link, screening for and avoiding use in patients with a history of pancreatitis, MTC, or a family history of Multiple Endocrine Neoplasia type 2 (MEN2) remains a mandatory precautionary measure (148)