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Slowness in movement ( bradykinesia ) Muscle rigidity, movement dysfunctions, and a reduction in dopamine-producing cells Poor Posture, Motor Function, or Postural Instability History of Parkinsons Disease & Paralysis Agitans In 1817, a British physician named James Parkinson described in his treatise An Essay on the Shaking Palsy the main symptoms of the disease, which was later named after him

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Because mTORC1 is a well-known regulator of metabolic functions, these findings imply that specific metabolic programs may underlie the unique characteristics of different B cell subsets