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More serious deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

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A study conducted on pregnant mice, the species with a very similar biological and behavioral makeup to humans, also found that B12 deficiency led to high cholesterol levels and a significant increase in body fat percentage in pregnant mice

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