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Costs and Incentives: Not all stakeholders have equal incentive

In summary, while oral GLP-1s will undoubtedly become a popular and vital pillar in treating diabetes and obesity, it is unrealistic to expect them to relegate subcutaneous formulations to a secondary role

SERT Ala56 mice that expressed an ASD-associated variant in humans exhibited elevations of 5-HT clearance in the brain and ASD-related social impairments and repetitive behavior, but forebrain 5-HT levels did not change in the mutants (149)

Layton C, Safa R, Osborne N

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