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Despite their differences, both drugs work by augmenting a hormone that controls blood sugar and appetite

These symptoms often resolve as the body adjusts to the medication over several weeks

It belongs to a class of medicines called GLP-1 receptor agonists, which mimic a natural hormone that regulates appetite and food intake

Studies suggest that these newer potassium binders allow patients to remain on RAASis in the treatment of chronic kidney disease and heart failure.[33,34] Consequences of discontinuing guideline-directed medical therapies RAASis and MRAs are both key disease-modifying agents for treating chronic kidney disease, cardiovascular disease, and diabetes mellitus.[35-37] They lead to increases in potassium concentration due to their interference with aldosterone (indirect and direct blockade), thus impairing excretion by the kidney

Studies of their long-term effectiveness and side effects are ongoing