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111 Erastin increases Fe 2+ levels and ROS production in breast cancer cells, promoting ferroptosis

Focusing on ferroptosis-related pathways, including the system Xc-/GSH/GPX4 axis, iron metabolism, and inflammatory cytokines, may provide novel therapeutic strategies for managing OA

To address this limitation, the study was re-conducted using an IMR-5 (MNA) xenograft immunodeficient NB mouse model, where a reduced toxicity was observed ( Figures 9A, C )

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