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Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and cmah-/-mdx mouse models of duchenne muscular dystrophy

This change in secretion was interpreted as a cellular response to mitigate the toxic buildup of Gb-3, involving mechanisms like enhanced p53 expression (121, 131)

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124 In 60 men with infertility participating in a placebo-controlled trial, 14 mg LactoLycopene (a readily absorbed form of lycopene) daily for 12 weeks improved sperm motility and morphology

The long-term biosafety of metal-based nanomedicines remains a concern due to the potential accumulation of metals in organs like the liver, spleen, and brain, which may lead to dose-dependent neurotoxicity and hepatotoxicity